Division I / Region 1
No. 8 Cleveland St. Ignatius (6-5) at No. 1 Lakewood St. Edward (9-1)
No. 7 McKinley (8-3) at No. 2 Austintown-Fitch (8-1)
No. 6 Strongsville (8-3) at No. 3 Mentor (8-2)
No. 5 Hudson (8-3) at No. 4 Jackson (8-2)
Division II / Region 7
No. 8 Whitehall-Yearling (9-2) at No. 1 Columbus Bishop Watterson (9-0)
No. 7 Louisville (9-2) at No. 2 Sunbury Big Walnut (10-0)
No. 6 Columbus St. Francis DeSales (8-3) at No. 3 Massillon (9-1)
No. 5 Canal Winchester (8-3) at No. 4 New Albany (8-2)
Division IV / Region 13
No. 8 Orrville (8-3) at No. 1 Streetsboro (8-2)
No. 7 Northwest (9-2) at No. 2 Rocky River (10-0)
No. 11 Poland Seminary (7-4) at No. 3 Beloit West Branch (9-1)
No. 5 Chesterland West Geauga (9-2) at No. 4 Norton (9-1)
Division V / Region 17
No. 9 Canton Central Catholic (7-4) at No. 1 Perry (10-0)
No. 7 Martins Ferry (10-1) at No. 2 Barnesville (10-0)
No. 6 Youngstown Cardinal Mooney (8-3) at No. 3 Girard (10-0)
No. 5 Conneaut (10-1) at No. 4 Garrettsville Garfield (10-0)
